In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...

Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...