Researchers at the University of California San Diego have developed a large-scale screening approach that identifies ...

The ability to control gene expression across a wide range is crucial for many fields, including bioengineering, disease detection, and environmental monitoring. Research led by Lingchong You, Ph.D., ...

An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with ...

The benefits of dietary fiber extend beyond digestive health, as dietary fiber-derived metabolites produced by gut microbiota ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...