Most of the cells in our body carry the genome, and those cells are constantly bombarded with environmental influences including UV rays, pollution, alcohol, and other exposures that can damage the ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...

ADP-ribosylation, the attachment of ADP-ribose to proteins, is a common eukaryotic post-translational modification. It exists in two forms: mono ADP-ribosylation (MARylation), where individual units ...

Deinococcus radiodurans is renowned for its extraordinary resistance to ionising radiation and other environmental stresses. This bacterium employs a combination of passive and active mechanisms to ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...