A protein thought to play a supporting role in DNA replication actually facilitates the whole process

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

Cells' built-in capacity limit for copying DNA could impact cancer treatment

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...
insider.si.edu

Concepts in eukaryotic DNA replication / edited by Melvin L. DePamphilis

Mechanisms for replicating DNA / G.S. Brush and T.J. Kelly -- Origins of DNA replication / M.L. DePamphilis -- Roles of transcription factors in DNA replication / P.C. van der Vliet -- Roles of ...
Science Daily

DNA replication mechanism in pluripotent stem cells

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...
mskcc.org

Cryo-Electron Microscopy Reveals Hidden Mechanics of DNA Replication, Sheds New Light on Cancer Target

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...
Medscape

The Future of Replication Stress and DNA Damage and Repair in Endometrial Cancer

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...