Chromatin-remodeling enzymes perform the formidable task of reorganizing the structure of a stable macromolecular assembly, the nucleosome. Recently published work demonstrates that the SNF2H ...
Chromatin-remodelling machines (remodellers) are large, multi-protein complexes that use the energy of ATP hydrolysis to mobilize and restructure nucleosomes. Nucleosomes wrap 146 bp of DNA in ∼1.7 ...
The nuclear receptor–binding SET Domain (NSD) family protein is closely connected with many cancers. However, their molecular mechanism remains unknown. Recently, SUSTech research team made new ...