γ-secretase may have been one of the first intramembrane proteases to be described, but since its discovery a host of these special cutters have been identified in organisms from bacteria on up. But ...

In a recent study posted to the Research Square preprint* server, a team of researchers investigated the toxicity and absorption, distribution, metabolism, and excretion (ADME) characteristics of a ...

The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through ...

Researchers at Nano Life Science Institute (WPI-NanoLSI) and the Cancer Research Institute at Kanazawa University have ...

Although many organisms capture and respond to sunlight, enzymes - proteins that catalyze biochemical reactions - are rarely driven by light. A new study captures the full cycle of complex structural ...