Explore the evolution of T-cell engagers, from experimental concepts to effective therapies for haematologic malignancies.
The thymus is a specialised primary lymphoid organ that underpins the development and education of T cells. Here, immature progenitors undergo a tightly regulated series of events that not only ...
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Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
By Hugo Francisco de Souza A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the ...
Ibrutinib was a breakthrough when it was first approved to treat R/R MCL in 2013, and a year later for patients with at least 1 prior treatment for chronic lymphocytic leukemia. However, its ...
The FDA has cleared the investigational new drug (IND) application for NPX372, a first-in-class T-cell engager (TCE) for the ...
Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...
The BBVA Foundation Frontiers of Knowledge Award in Biology and Biomedicine has gone in this eighteenth edition to Carl June ...
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