Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is ...

A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Conventional PCR systems require users to set a predetermined number of cycles based on assay- and sample-specific factors. When performing single-cell sequencing experiments, this requires knowledge ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...

In the canals, marshes, and swamps of the Florida Everglades, invasive fish are silently slipping into new waterways. Among them are the Asian swamp eel and the bullseye snakehead, two air-breathing ...

Alan Herbert, Founder and President of InsideOutBio, discusses the evolution of biological concepts related to DNA and protein structures ...

While the genes involved can differ, this example illustrates how most cancers arise. Accumulated DNA mutations, acquired either over time (ageing naturally leads to some DNA mistakes) or from ...

Content creator Jak White is breaking down the behind-the-scenes secrets of Bonnie Blue’s infamous “breeding” event. “I didn't expect it to be as busy. I think probably about 400 or 500 people were ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have overturned a long-standing assumption about how life begins at the molecular level. Using a ...

Tau hyperphosphorylation is linked to neurodegeneration in tauopathies including Alzheimer’s disease. Tau binds microtubules cooperatively to form cohesive tau envelopes, which are thought to control ...