New findings show that the genome’s 3D structure is constantly changing, with NIPBL guiding loop formation that regulates active genes. Faulty folding dynamics may underlie cancers and developmental ...

For decades, scientists viewed the genome of a newly fertilized egg as a structural "blank slate"—a disordered tangle of DNA ...

For many years, researchers believed that the DNA inside a newly fertilized egg began as a structural ‘blank slate’ – a loose ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...

Bruker now extends their complete biology approach to mouse research by announcing development of the CosMx Mouse Whole ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Retrotransposons are pivotal in human genome evolution, driving structural variation and regulatory innovation while influencing health and disease.

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...