Abstract Reliable and cost-effective detection of single-stranded circulating cell-free DNA (ss-cfDNA) is crucial for liquid biopsies, offering a ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...

Alan Herbert, Founder and President of InsideOutBio, discusses the evolution of biological concepts related to DNA and protein structures ...

Scientists published direct mapping of the retrotransposon enzyme's activity, advancing understanding of genetic elements that can alter DNA sequences.