Living cells are sustained by countless chemical reactions that must be carefully regulated to maintain internal order and ...

Robert Shepherd, a Ph.D. student in the Sanchez Lab, was the lead author of the paper published on February 5 describing a new high-throughput assay. A team of biochemists at the University of ...

Content Catalyst, the leading technology partner for market insight publishers, today announced the launch of DocuViewer, a new feature that delivers PDF and PowerPoint research content through a ...

Worldwide Clinical Trials is expanding its horizons with the acquisition of Catalyst Clinical Research, a specialist oncology organization with a particular knack for early-stage cancer trials. The ...

Trian and General Catalyst will pay $49 per share in cash, valuing Janus at about $7.4 billion. That represents a 6.5% premium to Janus' Friday's close. The deal is expected to close in mid-2026, they ...

The snapshots reveal key reactions steps. At 0 ms, water molecules occupy the substrate-binding site. At 50 ms, a substrate-cofactor intermediate forms. At 100 ms, the product is released, and the ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Researchers from the lab of Nobel laureate, David Baker, PhD, have now released RFdiffusion3 open source. The latest version of the de novo protein design model generates proteins that interact with ...

Structure of a twisting BINOL radical shown with a P450 enzyme in the background. A BINOL radical twists within a P450 enzyme. Credit: S. Luke Schulert Students of stereochemistry know that chirality ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...