A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing.

Hundreds of different types of mutations in these genes have been identified, some of which have been determined to be harmful, while others have no proven impact. Harmful mutations in these genes …

BRCA1 (BReast CAncer gene 1) is a gene that, when mutated, is associated with an increased risk of several cancers including breast cancer, and, particularly, triple-negative breast cancer (TNBC).

Apr 1, 2025 · When a BRCA gene is mutated, it may no longer be effective at repairing broken DNA and helping to prevent breast cancer. Because of this, people with a BRCA gene mutation are more likely …

Mutations in the BRCA1 and BRCA2 genes increase your risk for breast, ovarian and other cancers. A breast medical oncologist and a genetic counselor share what to know after learning you carry a …

Women who have a BRCA1 or BRCA2 (BRCA1/2) inherited gene mutation have an increased risk of breast cancer and ovarian cancer. Estimates of these risks vary greatly.

Oct 20, 2025 · Have you undergone genetic testing and learned you have a BRCA gene mutation? If so, you may be worried about what’s next.

Everyone has two types of breast cancer (“BRCA”) genes in every cell of their body. When functioning properly, BRCA1 and BRCA2 repair DNA, keep other genes healthy, and prevent cancerous …

Dec 23, 2025 · Harmful changes in the genes can increase the risk of cancer. Healthcare professionals sometimes call these gene changes variants or mutations. The BRCA gene test looks for changes in …

Nov 21, 2025 · Healthy BRCA1 and BRCA2 genes stop tumors from growing. But mutations in these genes may lead to breast cancer and other types of cancer. You may have heard about the genes …